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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1829 1
1870 1
1877 1
1900 1
1916 1
1917 1
1921 1
1924 2
1927 2
1930 1
1941 2
1945 2
1946 2
1947 7
1948 7
1949 4
1950 3
1951 2
1952 4
1953 4
1954 7
1955 8
1956 12
1957 11
1958 11
1959 12
1960 8
1961 13
1962 5
1963 14
1964 13
1965 27
1966 25
1967 29
1968 37
1969 30
1970 38
1971 57
1972 49
1973 59
1974 76
1975 275
1976 354
1977 311
1978 418
1979 457
1980 557
1981 643
1982 790
1983 988
1984 1189
1985 1386
1986 1437
1987 1591
1988 1778
1989 2154
1990 2464
1991 2731
1992 3237
1993 3543
1994 4026
1995 4309
1996 5008
1997 5254
1998 5832
1999 6090
2000 6663
2001 6790
2002 6908
2003 7277
2004 7814
2005 8355
2006 8602
2007 8713
2008 8841
2009 9227
2010 9608
2011 10574
2012 11236
2013 11488
2014 11769
2015 11990
2016 12153
2017 12120
2018 12361
2019 12962
2020 13960
2021 14286
2022 13067
2023 12092
2024 4383

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283,522 results

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Page 1
Evolution and folding of repeat proteins.
Galpern EA, Marchi J, Mora T, Walczak AM, Ferreiro DU. Galpern EA, et al. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2204131119. doi: 10.1073/pnas.2204131119. Epub 2022 Jul 29. Proc Natl Acad Sci U S A. 2022. PMID: 35905321 Free PMC article.
Repeat proteins are made with tandem copies of similar amino acid stretches that fold into elongated architectures. ...Here, we propose a scheme to map evolutionary information at the sequence level to a coarse-grained model for repeat-protein folding and use it to
Repeat proteins are made with tandem copies of similar amino acid stretches that fold into elongated architectures. ...Here, we propo
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
Khristich AN, Mirkin SM. Khristich AN, et al. J Biol Chem. 2020 Mar 27;295(13):4134-4170. doi: 10.1074/jbc.REV119.007678. Epub 2020 Feb 14. J Biol Chem. 2020. PMID: 32060097 Free PMC article. Review.
We then survey alternative DNA structures that are formed by expandable repeats and review the evidence that formation of these structures is at the core of repeat instability. Next, we describe the consequences of the presence of long structure-forming repeats
We then survey alternative DNA structures that are formed by expandable repeats and review the evidence that formation of these struc …
The Effect of Mutations in the TPR and Ankyrin Families of Alpha Solenoid Repeat Proteins.
Izert MA, Szybowska PE, Górna MW, Merski M. Izert MA, et al. Front Bioinform. 2021 Jul 6;1:696368. doi: 10.3389/fbinf.2021.696368. eCollection 2021. Front Bioinform. 2021. PMID: 36303725 Free PMC article. Review.
Protein repeats are short, highly similar peptide motifs that occur several times within a single protein, for example the TPR and Ankyrin repeats. ...To address this issue, we review the effects of mutations in a number of natural repeat proteins from the te …
Protein repeats are short, highly similar peptide motifs that occur several times within a single protein, for example the TPR and An …
CAC--the neglected repeat.
Sertedaki A, Lindsay S. Sertedaki A, et al. Bioessays. 1996 Mar;18(3):237-42. doi: 10.1002/bies.950180311. Bioessays. 1996. PMID: 8867738 Review.
Here we review the information available about one type of repetitive DNA, the trinucleotide repeat (CAC)n, and briefly compare it with other trinucleotide repeats. ...From the data that is available, it is clear that there are at least two areas that should repay f …
Here we review the information available about one type of repetitive DNA, the trinucleotide repeat (CAC)n, and briefly compare it wi …
Progress on the mechanistic research of the trinucleotide repeat instabilities underlying human neurodegenerative diseases.
Lv KN, Pan XF. Lv KN, et al. Yi Chuan. 2021 Sep 20;43(9):835-848. doi: 10.16288/j.yczz.21-182. Yi Chuan. 2021. PMID: 34702697 Review.
Human genetical studies also suggest that abnormal DNA replication, repair, recombination, or gene transcription that occurred in the disease-related trinucleotide repeat DNA sites may play a key role in the trinucleotide repeat DNA instabilities. Based on the resea …
Human genetical studies also suggest that abnormal DNA replication, repair, recombination, or gene transcription that occurred in the diseas …
Expansion and Function of Repeat Domain Proteins During Stress and Development in Plants.
Sharma M, Pandey GK. Sharma M, et al. Front Plant Sci. 2016 Jan 11;6:1218. doi: 10.3389/fpls.2015.01218. eCollection 2015. Front Plant Sci. 2016. PMID: 26793205 Free PMC article. Review.
Several repeat protein gene families have been identified in plants. Such as Armadillo (ARM), Ankyrin (ANK), HEAT, Kelch-like repeats, Tetratricopeptide (TPR), Leucine rich repeats (LRR), WD40, and Pentatricopeptide repeats (PPR). The structure and fun …
Several repeat protein gene families have been identified in plants. Such as Armadillo (ARM), Ankyrin (ANK), HEAT, Kelch-like repe
Squaring up to DNA: pentapeptide repeat proteins and DNA mimicry.
Shah S, Heddle JG. Shah S, et al. Appl Microbiol Biotechnol. 2014 Dec;98(23):9545-60. doi: 10.1007/s00253-014-6151-3. Epub 2014 Oct 26. Appl Microbiol Biotechnol. 2014. PMID: 25343976 Review.
Pentapeptide repeats are a class of proteins characterized by the presence of multiple repeating sequences five amino acids in length. ...DNA gyrase-targeting pentapeptide repeat proteins can both inhibit DNA gyrase-a potentially useful therapeutic property-a …
Pentapeptide repeats are a class of proteins characterized by the presence of multiple repeating sequences five amino acids in …
Topological characteristics of helical repeat proteins.
Groves MR, Barford D. Groves MR, et al. Curr Opin Struct Biol. 1999 Jun;9(3):383-9. doi: 10.1016/s0959-440x(99)80052-9. Curr Opin Struct Biol. 1999. PMID: 10361086 Review.
The recent elucidation of protein structures based upon repeating amino acid motifs, including the armadillo motif, the HEAT motif and tetratricopeptide repeats, reveals that they belong to the class of helical repeat proteins. These proteins share the common …
The recent elucidation of protein structures based upon repeating amino acid motifs, including the armadillo motif, the HEAT motif an …
WarpSTR: determining tandem repeat lengths using raw nanopore signals.
Sitarčík J, Vinař T, Brejová B, Krampl W, Budiš J, Radvánszky J, Lucká M. Sitarčík J, et al. Bioinformatics. 2023 Jun 1;39(6):btad388. doi: 10.1093/bioinformatics/btad388. Bioinformatics. 2023. PMID: 37326967 Free PMC article.
MOTIVATION: Short tandem repeats (STRs) are regions of a genome containing many consecutive copies of the same short motif, possibly with small variations. ...Basecalling of nanopore reads is however particularly unreliable in repeating regions, and therefore direct …
MOTIVATION: Short tandem repeats (STRs) are regions of a genome containing many consecutive copies of the same short motif, possibly …
283,522 results
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